Opportunity Information: Apply for CDC RFA GH 23 0019
This funding opportunity (CDC RFA GH 23 0019) is a PEPFAR-supported cooperative agreement from the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), focused on strengthening and expanding the DREAMS program in Zimbabwe. DREAMS stands for Determined, Resilient, Empowered, AIDS-Free, Mentored, and Safe, and its core purpose is to reduce new HIV infections among adolescent girls and young women (AGYW) by delivering a layered, evidence-based package of HIV prevention and related support services. Rather than relying on a single intervention, DREAMS is built around a combination prevention approach that addresses the interconnected biological, socioeconomic, cultural, and structural factors that increase HIV vulnerability for AGYW, with the broader goal of contributing to HIV epidemic control.
Funding for the first year is described in a specific way: the listed award ceiling for Year 1 is shown as 0 (none), while CDC indicates an anticipated total Fiscal Year funding amount of about $10,000,000 for Year 1, contingent on the availability of funds. CDC expects to make two awards under this announcement. The opportunity is categorized as discretionary funding, the instrument type is a cooperative agreement (meaning CDC will likely have substantial involvement in program direction and oversight compared with a standard grant), and it falls under the health funding activity category (CFDA/Assistance Listing 93.067). Eligibility is described as unrestricted, meaning a wide range of organization types may apply, subject to any additional eligibility clarifications contained in the full announcement.
Programmatically, the recipient or recipients are expected to do two big things at once: consolidate DREAMS implementation in four districts where activities are already underway, and expand the program to new districts. Decisions about where to expand are not arbitrary; they are expected to align with PEPFAR guidance and be informed by current epidemiologic data, survey findings, contextual considerations, and routine monitoring indicators. This signals a strong emphasis on data-driven geographic prioritization and adaptive planning, so that resources follow need and demonstrated HIV risk.
Within both existing and new districts, the DREAMS model is explicitly meant to reach AGYW who are most vulnerable to HIV, not just the general population of young women. Applicants are therefore expected to have credible methods to identify, recruit, and enroll the AGYW at highest risk and, importantly, to retain them in services over time. Retention matters because DREAMS is designed as a sustained, multi-component package, and the protective impact depends on participants actually receiving a meaningful set of interventions rather than a one-time contact.
The intervention expectations cover several layers. For AGYW directly, recipients are to implement evidence-based HIV prevention and violence prevention interventions aimed at reducing HIV risk, recognizing that exposure to violence and power imbalances can directly increase vulnerability and reduce access to prevention options. For parents and families of vulnerable AGYW, recipients must deliver evidence-based HIV prevention, violence prevention, and economic strengthening interventions. This reflects the program logic that family stability, caregiver engagement, and household economic resilience can reduce reliance on high-risk coping strategies, improve school participation, and strengthen protective environments for girls and young women.
At the community level, the opportunity calls for addressing structural barriers and harmful social norms. In practice, this typically means coordinated community engagement to reduce stigma, shift norms that tolerate gender-based violence or age-disparate relationships, and improve community support for girls staying in school, accessing health services, and exercising agency in relationships. Finally, the announcement highlights the need to refine and strengthen mentorship and coaching approaches to sustain DREAMS achievements. Mentorship is central to DREAMS because trusted mentors can improve program adherence, support behavior change, connect AGYW to services, and help maintain gains after initial enrollment.
Key administrative details from the notice include the funding opportunity title as listed, the sponsoring agency (CDC within HHS), the creation date (January 12, 2023), and the original application closing date (March 13, 2023), with electronic submissions due by 11:59 pm Eastern Time on the deadline. Overall, the opportunity is geared toward organizations that can manage a multi-district, data-informed scale-up of a comprehensive HIV prevention platform for AGYW, while also coordinating family- and community-level interventions and building durable mentorship systems that keep young women engaged and protected over time.Apply for CDC RFA GH 23 0019
- The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Strengthening an Integrated Comprehensive Approach for HIV Services for Adolescents and Young People through Determined, Resilient, AIDS-Free Mentored and Safe (DREAMS) Program in Zimbabwe under the President's Emergency Plan for AIDS Relief (PE" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
- This funding opportunity was created on Jan 12, 2023.
- Applicants must submit their applications by Mar 13, 2023 Electronically submitted applications must be submitted no later than 1159 pm ET on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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| Strengthening Laboratory Systems that Support Diagnosis, Treatment, Prevention, and Management of HIV/AIDS and Related Public Health Diseases in the Republic of South Sudan under the President's Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH 23 0035 Funding Number: CDC RFA GH 23 0035 Agency: Department of Health and Human Services, Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
| Exploring Preferences for Long-Acting Antiretroviral Therapies (LA-ART) in a Community-Based Sample of Priority Populations Living with HIV Who are Disproportionately Affected Apply for RFA PS 23 003 Funding Number: RFA PS 23 003 Agency: Department of Health and Human Services, Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $333,000 |
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| Increasing PrEP Use Among Disproportionately Affected Populations in the United States Apply for RFA PS 23 001 Funding Number: RFA PS 23 001 Agency: Department of Health and Human Services, Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $2,000,000 |
| First Responders – Comprehensive Addiction and Recovery Act Apply for TI 23 012 Funding Number: TI 23 012 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $800,000 |
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| Community Programs for Outreach and Intervention with Youth and Young Adults at Clinical High Risk for Psychosis Apply for SM 23 014 Funding Number: SM 23 014 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $400,000 |
| Grants for the Benefit of Homeless Individuals Apply for TI 23 005 Funding Number: TI 23 005 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $500,000 |
| The Sudden Unexpected Infant Death (SUID) and Sudden Death in the Young (SDY) Case Registry Apply for CDC RFA DP 23 0006 Funding Number: CDC RFA DP 23 0006 Agency: Department of Health and Human Services, Centers for Disease Control - NCCDPHP Category: Health Funding Amount: Case Dependent |
| Linking Actions for Unmet Needs in Children’s Health Grant Program (Project LAUNCH) Apply for SM 23 004 Funding Number: SM 23 004 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $800,000 |
| The High Obesity Program (HOP) Apply for CDC RFA DP 23 0013 Funding Number: CDC RFA DP 23 0013 Agency: Department of Health and Human Services, Centers for Disease Control - NCCDPHP Category: Health Funding Amount: $1,200,000 |
| Urban Indian 4-in-1 Grant Program Apply for HHS 2023 IHS UIHP2 0001 Funding Number: HHS 2023 IHS UIHP2 0001 Agency: Department of Health and Human Services, Indian Health Service Category: Health Funding Amount: $249,360 |
| BOLD Public Health Programs to Address Alzheimer’s Disease and Related Dementias Apply for CDC RFA DP 23 0010 Funding Number: CDC RFA DP 23 0010 Agency: Department of Health and Human Services, Centers for Disease Control - NCCDPHP Category: Health Funding Amount: Case Dependent |
| Comprehensive Provision of Integrated, High-Quality Community- and Facility-Based HIV and Tuberculosis (TB) Services in Namibia under the President's Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH 23 0005 Funding Number: CDC RFA GH 23 0005 Agency: Department of Health and Human Services, Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
| Integrated Substance Use Disorder Training Program (ISTP) Apply for HRSA 23 090 Funding Number: HRSA 23 090 Agency: Department of Health and Human Services, Health Resources and Services Administration Category: Health Funding Amount: $515,000 |
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| Services Program for Residential Treatment for Pregnant and Postpartum Women Apply for TI 23 002 Funding Number: TI 23 002 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $525,000 |
| Improving Access to Overdose Treatment Apply for TI 23 004 Funding Number: TI 23 004 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $200,000 |
| State Pilot Program for Treatment for Pregnant and Postpartum Women Apply for TI 23 003 Funding Number: TI 23 003 Agency: Department of Health and Human Services, Substance Abuse and Mental Health Services Adminis Category: Health Funding Amount: $900,000 |
| Sustain and Accelerate a Comprehensive HIV Response in the United Republic of Tanzania under the President's Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH 23 0022 Funding Number: CDC RFA GH 23 0022 Agency: Department of Health and Human Services, Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
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