Opportunity Information: Apply for RFA MH 25 185
The National Institutes of Health (NIH) is offering a discretionary research grant opportunity titled "Advancing HIV service delivery through pharmacies and pharmacists (R01 Clinical Trial Optional)" under funding opportunity number RFA-MH-25-185. This Notice of Funding Opportunity (NOFO) supports research aimed at strengthening and expanding the role of pharmacists and pharmacies in delivering HIV services, with an emphasis on making those services easier to access, more equitable, and more effective. The work can be conducted in the United States and/or in global settings, reflecting an interest in approaches that are adaptable across different health systems, communities, and resource environments.
At its core, the NOFO is focused on research that helps capacitate, transform, and scale HIV testing, prevention, and care through pharmacy-based pathways. That means the NIH is looking for projects that do more than test small, isolated ideas; it is encouraging research that can build the practical ability of pharmacy personnel and pharmacy systems to deliver the full spectrum of HIV-related services, and then support broader implementation. Examples of the kinds of HIV services implied here include HIV testing and linkage to care, prevention services such as PrEP-related support (where relevant), and ongoing care support activities that pharmacies may be well positioned to provide due to convenience, extended hours, and frequent patient touchpoints.
A major theme in the NOFO is workforce and system readiness, particularly through training and education. The announcement specifically calls out the advancement of training curricula to enable pharmacy students, practicing pharmacists, pharmacies, and larger pharmacy systems to deliver HIV services "with ease, equity, and effectiveness." In practice, this points to research that develops, refines, and evaluates educational and training approaches, implementation supports, workflow redesign, clinical decision support, referral and linkage models, and other strategies that help pharmacy teams consistently provide HIV services without creating unnecessary burden or widening disparities. The explicit mention of equity signals that applicants should be attentive to who benefits from pharmacy-based HIV service delivery, including groups disproportionately affected by HIV and communities with barriers to traditional clinic-based care.
This NOFO uses the R01 grant mechanism and is labeled "Clinical Trial Optional," meaning applicants may propose studies that include clinical trials if appropriate, but a clinical trial is not required. The R01 mechanism generally fits projects that already have preliminary data and are ready for more definitive, larger-scale evaluations, including large-scale clinical trials, robust implementation studies, or longitudinal analyses that examine outcomes over time. The NOFO also references a companion opportunity using the R21 mechanism (RFA-MH-25-186), which is better suited to earlier-stage projects such as pilots or novel interventions that do not yet have substantial preliminary data. In other words, RFA-MH-25-185 (R01) is positioned for more mature research programs that can justify scale, rigor, and longer arcs of evaluation.
Eligibility for this opportunity is broad and includes many types of organizations that could lead pharmacy- and community-centered HIV research. Eligible applicants include state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations that are not federally recognized; public housing authorities/Indian housing authorities; nonprofit organizations (both with and without 501(c)(3) status); for-profit organizations (other than small businesses); and small businesses. The NOFO further highlights additional eligible groups such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, U.S. territories or possessions, regional organizations, and non-U.S. entities (foreign organizations). This wide eligibility signals an intent to encourage partnerships that bring together academic researchers, community organizations, health systems, and pharmacy sector stakeholders, including those embedded in underserved settings.
The opportunity is categorized as a grant within a broad set of funding activity areas that include health and social services, and it is associated with multiple CFDA numbers (including 93.233, 93.242, 93.273, 93.279, 93.307, 93.310, and several others listed in the source data), reflecting NIH programmatic alignment across related health research and service delivery priorities. The original closing date listed for applications is 2024-08-13, and the announcement was created on 2024-04-29. The source data does not specify an award ceiling or the expected number of awards, so applicants would typically look to the full NOFO in NIH systems for budget expectations, project period details, review criteria, and any institute- or program-specific priorities tied to this funding opportunity.
Overall, this NOFO is aimed at generating practical, scalable evidence on how pharmacies and pharmacists can play a larger, more consistent role in HIV testing, prevention, and care, while also building the training and system supports needed to make pharmacy-based HIV service delivery sustainable and equitable in real-world settings.Apply for RFA MH 25 185
- The National Institutes of Health in the education, food and nutrition, health, income security and social services sector is offering a public funding opportunity titled "Advancing HIV service delivery through pharmacies and pharmacists (R01 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.233, 93.242, 93.273, 93.279, 93.307, 93.310, 93.837, 93.838, 93.839, 93.840, 93.847, 93.855, 93.865.
- This funding opportunity was created on 2024-04-29.
- Applicants must submit their applications by 2024-08-13. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is the name of this NIH funding opportunity?
The opportunity is titled "Advancing HIV service delivery through pharmacies and pharmacists (R01 Clinical Trial Optional)."
What is the funding opportunity number?
The funding opportunity number is RFA-MH-25-185.
Which agency is offering this grant?
This is a discretionary research grant opportunity offered by the National Institutes of Health (NIH).
What is the main goal of this NOFO?
The main goal is to support research that strengthens and expands the role of pharmacists and pharmacies in delivering HIV services in ways that improve access, promote equity, and increase effectiveness.
What kinds of HIV services are intended to be supported through pharmacy-based pathways?
The NOFO emphasizes research related to HIV testing and linkage to care, HIV prevention services (including PrEP-related support where relevant), and ongoing care support activities that pharmacies may be positioned to provide due to convenience, extended hours, and frequent patient touchpoints.
Is this opportunity focused on small pilot ideas or larger-scale work?
It is oriented toward research that can capacitate, transform, and scale HIV testing, prevention, and care through pharmacy-based pathways, rather than only testing small, isolated ideas.
What does "capacitate, transform, and scale" mean in the context of this NOFO?
Based on the description provided, it points to building practical ability within pharmacy personnel and pharmacy systems to deliver HIV services, and then supporting broader implementation across settings and systems.
Does the NOFO emphasize training and education?
Yes. A major theme is workforce and system readiness through training and education, including advancing training curricula for pharmacy students, practicing pharmacists, pharmacies, and larger pharmacy systems to deliver HIV services "with ease, equity, and effectiveness."
What types of strategies might be researched under this NOFO?
The description highlights research that develops, refines, and evaluates educational and training approaches, implementation supports, workflow redesign, clinical decision support, and referral and linkage models, as well as other strategies that help pharmacy teams provide HIV services consistently without unnecessary burden or widening disparities.
How is equity addressed in this opportunity?
Equity is an explicit emphasis, signaling that research should be attentive to who benefits from pharmacy-based HIV service delivery, including groups disproportionately affected by HIV and communities that face barriers to traditional clinic-based care.
Where can the research be conducted?
The work can be conducted in the United States and/or in global settings, reflecting interest in approaches adaptable across different health systems, communities, and resource environments.
What grant mechanism is used for this opportunity?
This NOFO uses the R01 grant mechanism.
What does "Clinical Trial Optional" mean here?
"Clinical Trial Optional" means applicants may propose studies that include clinical trials if appropriate, but a clinical trial is not required.
What kinds of projects are typically a good fit for an R01 in this context?
The description indicates the R01 generally fits projects with preliminary data that are ready for more definitive, larger-scale evaluation, including large-scale clinical trials, robust implementation studies, or longitudinal analyses examining outcomes over time.
Is there a related NIH opportunity for earlier-stage or pilot projects?
Yes. The NOFO references a companion opportunity using the R21 mechanism (RFA-MH-25-186), described as better suited to earlier-stage projects such as pilots or novel interventions that do not yet have substantial preliminary data.
Who is eligible to apply?
Eligibility is broad and includes state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations that are not federally recognized; public housing authorities/Indian housing authorities; nonprofit organizations (with or without 501(c)(3) status); for-profit organizations (other than small businesses); and small businesses.
Are community-based and faith-based organizations eligible?
Yes. The NOFO highlights faith-based or community-based organizations as eligible.
Are minority-serving institutions specifically mentioned as eligible?
Yes. The NOFO highlights Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs).
Are U.S. territories or possessions included in eligible applicants?
Yes. U.S. territories or possessions are specifically highlighted among eligible groups.
Are non-U.S. (foreign) organizations eligible to apply?
Yes. The NOFO explicitly includes non-U.S. entities (foreign organizations) among eligible applicants.
Does the opportunity encourage partnerships?
The wide eligibility is described as signaling an intent to encourage partnerships among academic researchers, community organizations, health systems, and pharmacy sector stakeholders, including those in underserved settings.
What broad funding activity areas is this opportunity associated with?
It is categorized as a grant within broad funding activity areas that include health and social services.
Are CFDA numbers associated with this opportunity?
Yes. The opportunity is associated with multiple CFDA numbers, including 93.233, 93.242, 93.273, 93.279, 93.307, and 93.310, among others listed in the source data.
What is the original closing date for applications?
The original closing date listed is 2024-08-13.
When was the announcement created?
The announcement was created on 2024-04-29.
Does the provided information specify an award ceiling or the number of awards?
No. The source data described does not specify an award ceiling or the expected number of awards.
Where should applicants look for budget expectations, project period details, and review criteria?
The information indicates applicants would typically look to the full NOFO in NIH systems for budget expectations, project period details, review criteria, and any institute- or program-specific priorities tied to this opportunity.
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